Easy, Natural Remedies To Help With Multiple Sclerosis Fatigue
Fatigue is hands-down one of the most frustrating symptoms of multiple sclerosis (MS). It’s not just being “a little tired.” It’s that bone-deep exhaustion that makes even small tasks feel impossible. If you’ve ever wondered, "Does MS cause fatigue?" or "What helps with multiple sclerosis fatigue?"—you’re in the right place.
The good news? There are natural ways to boost your energy and address the root causes of MS fatigue, rather than just pushing through another day running on empty.
Let’s dive in.
Why Does MS Cause Fatigue?
First, let’s clear something up—MS-related fatigue isn’t just about being tired. This kind of exhaustion is different from what a good night’s sleep can fix.
MS fatigue happens because:
Nerve damage slows down energy production. Your nervous system is working overtime to compensate for damaged pathways, which drains your energy faster.
Mitochondrial dysfunction reduces cellular energy. Your mitochondria (the tiny powerhouses in your cells) aren’t producing energy efficiently.
Chronic inflammation forces your body to fight 24/7. When your immune system is in overdrive, energy gets funneled toward fighting inflammation instead of daily function.
Hidden infections and viruses like Epstein-Barr (EBV) can reactivate. Research shows that viruses lingering in your system can worsen MS symptoms, including fatigue.
Nervous system dysregulation keeps your body stuck in stress mode. If your system is constantly in fight-or-flight, your energy reserves burn out quickly.
The key to managing MS fatigue? Supporting energy production, calming inflammation, and addressing hidden root causes.
Natural Remedies for MS Fatigue
1. Prioritizing Restful Sleep
If your sleep is off, your energy will be too. Try:
✔ Keeping a consistent bedtime
✔ Avoiding blue light from screens before bed
✔ Using magnesium or herbal teas (like chamomile or passionflower) to promote relaxation
Bonus tip: If you wake up feeling unrefreshed, you may not be getting enough deep sleep. Tracking your sleep quality with an app like Oura or Whoop can be a game-changer.
2. Supporting Mitochondrial Health
MS fatigue often links back to mitochondrial dysfunction, meaning your cells aren’t producing energy the way they should. Supporting mitochondria can make a massive difference.
Try adding:
✔ CoQ10 & PQQ – Help boost ATP (your body’s main energy currency)
✔ Alpha-lipoic acid – Supports mitochondrial function and reduces nerve damage
✔ Acetyl-L-Carnitine – Helps shuttle fat into mitochondria for fuel
3. Managing Stress & Nervous System Regulation
Your nervous system plays a huge role in fatigue. Chronic stress and nervous system dysregulation can drain your energy reserves before you even get out of bed.
Helpful strategies include:
✔ Practicing breathwork (like box breathing or vagus nerve exercises)
✔ Grounding techniques – Walking barefoot on the grass, spending time in nature
✔ Herbs like ashwagandha & rhodiola – Help regulate cortisol and improve resilience
4. Eating to Reduce Inflammation
Inflammation is one of the biggest drivers of MS fatigue. Certain foods can fuel inflammation, while others help calm it down.
✔ Eat more: Wild-caught fish, olive oil, leafy greens, turmeric, berries
✔ Reduce: Processed foods, sugar, gluten (especially if sensitive), industrial seed oils
Pro tip: Try incorporating broccoli sprouts for their sulforaphane content—an incredible compound that supports detoxification and inflammation reduction.
5. Addressing Hidden Viral or Bacterial Infections
Many MS patients have reactivated Epstein-Barr virus (EBV) or other chronic infections draining their energy. Some natural ways to support your immune system:
✔ Monolaurin & lysine – Help inhibit viral replication
✔ Zinc & vitamin C – Support immune function
✔ Reishi mushroom – A powerful adaptogen that helps regulate immune response
If you suspect underlying infections, getting tested for EBV, mycoplasma, or Lyme may be worth exploring.
6. Moving Your Body (The Right Way!)
Too much exercise can leave you wiped out, but gentle movement actually helps MS fatigue. The key is finding the right type and intensity for your body.
✔ Try walking, yoga, or swimming instead of high-intensity workouts
✔ Listen to your body – If you crash after exercising, scale it back
✔ Incorporate lymphatic support – Rebounding (mini trampoline) or dry brushing can help with circulation and detox
Addressing the Root Causes of MS Fatigue
While lifestyle changes can make a huge impact, digging deeper into root causes is what truly creates lasting energy shifts.
MS shares many similarities with chronic fatigue syndrome and Long COVID, meaning some of the same root causes apply, including:
🦠 Hidden infections – Viruses like EBV, chronic Lyme, or mold exposure can keep your immune system stuck in overdrive. Testing for these can reveal deeper issues.
🔋 Mitochondrial dysfunction – If your cells aren’t making enough energy, fatigue will always be an issue. Supporting mitochondria with CoQ10, PQQ, and NAD+ can help.
🔥 Chronic inflammation – Whether from gut imbalances, food sensitivities, or environmental toxins, lowering inflammation is key for improving fatigue.
🧠 Nervous system dysregulation – When your body is stuck in stress mode, energy production tanks. Brain rewiring exercises, meditation, and vagus nerve stimulation can help.
By addressing these deeper layers, you give your body the tools it needs to heal—naturally.
Final Thoughts
If you’re dealing with multiple sclerosis fatigue, you’re not alone—and you don’t have to accept exhaustion as your normal.
By making small, intentional changes—supporting your mitochondria, balancing inflammation, and addressing underlying infections—you can start feeling like yourself again.
And remember, healing takes time. Be patient with yourself, celebrate small wins, and know that energy is something you can rebuild.
Need More Support?
If you’re looking for personalized strategies to help with MS fatigue, I’d love to support you. Schedule a free discovery call to dive deeper into what’s really going on in your body and create a plan that works for you.